https://www.selleckchem.com/pr....oducts/navoximod.htm
Autoimmune uveitis is a sight-threatening intraocular inflammatory disease. For 30 years, the mouse model of experimental autoimmune uveitis has been employed to investigate disease mechanisms and test immunotherapeutic approaches. However, inflammation in this model is self-limited, and does not ****te the chronic, insidious nature prevalent in the human disease. Herein, a robust and reliable model of chronic autoimmune uveitis was developed and characterized in two strains of wild-type mice by modifying interphotoreceptor ret