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BACKGROUND Carbapenemase-producing Enterobacterales (CPE) represents a serious threat to public health. Clinical microbiology laboratories (CML) need effective protocols for screening and confirmation of CPE. AIM To prospectively evaluate an algorithm for the screening of carbapenemase-producing Klebsiella pneumoniae in an OXA-48 endemic hospital. METHODS The algorithm was based on a disc diffusion assay using ertapenem and temocillin, which also served as a purity check for routine automated antimicrobial susceptibility testing. All i
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