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We highlight the need for continuous investigation of chordoma regression to uncover the underlying mechanisms. The present reported case is somehow different from previous ones and does not share an underlying inflammatory/immunological recognizable fact, being interpreted by us as a spontaneous partial regression of the tumor. We highlight the need for continuous investigation of chordoma regression to uncover the underlying mechanisms. The use of thrombin-based hemostatic agents (TBHAs) has become common practice in most neurosurgica
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