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Background The objective of this study was to assess the relationship between inflammation-based scores and prognosis of patients who had undergone mechanical thrombectomy (MT) for large artery occlusion (LAO). Methods A total of 411 patients were enrolled and inflammation-based scores, such as neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) were calculated based on laboratory data. Prognoses were evaluated with unfavorable outcome (modified