https://www.selleckchem.com/pr....oducts/Phlorizin(Phl
Triple-positive Tregs exhibited higher TCR diversity and a tumor-resident phenotype. Triple-positive TIL showed superior prognostic impact relative to TIL expressing other combinations of these markers. TIGIT was uniquely upregulated on triple-positive CD8 effector cells relative to their CD4 Treg counterparts. Coexpression of CD39, CD103, and PD-1 demarcates highly activated CD8 and CD4 TIL with inferred roles in cytolytic, humoral, and regulatory immune functions. Triple-positive TIL demonstrate exceptional prognostic si