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Food pantries are community-based organizations that provide food to prevalently low and very low food secure households, presenting an opportune point of contact and potential site for interventions. This review evaluates the food security, dietary quality, dietary intake and health outcomes of U.S. adults served by food pantries and the potential for interventions based in food pantries to improve these outcomes. Results from the 15 included studies showed the prevalence of food insecurity and very low food security among food pantry c