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No perceptible variations in pulmonary function tests emerged after 20, 40, or 60 hyperbaric oxygen therapy sessions. Indeed, a subgroup analysis of the cohort, stratified by pre-existing respiratory diseases, smoking history, and treatment pressure, revealed no significant shifts in pulmonary function tests during HBOT. Serial hyperbaric oxygen therapy (HBOT) sessions, regardless of pre-existing respiratory conditions, did not produce any substantial long-term changes