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Universal adhesive compositions and the corresponding adhesive strategy could substantially influence the effectiveness and longevity of the bond. This investigation aimed to quantify microtensile bond strength (TBS) and nanoleakage (NL), both initially and after 6 months of aging, and also determine the in situ degree of conversion (DC) of two universal adhesives (Scotchbond Universal Adhesive, SBU; Xeno Select, XEN), utilizing etch-and-rinse (ER) and self-etch (