https://www.selleckchem.com/pr....oducts/XL765(SAR2454
BACKGROUND Coronavirus 229E (HCoV-229E), one of the causes of the common cold, exacerbates chronic obstructive pulmonary disease (COPD) and bronchial asthma. Long-acting muscarinic antagonists and β2-agonists and inhaled corticosteroids inhibit the exacerbation of COPD and bronchial asthma caused by infection with viruses, including HCoV-229E. However, the effects of these drugs on HCoV-229E ****tion and infection-induced inflammation in the human airway are unknown. METHODS Primary human nasal (HNE) and tracheal (HTE) epith