https://wz811antagonist.com/sh....ort-term-effect-of-b
A deficit of the enzyme Cathepsin K, essential for osteoclast function in bone resorption, is the root cause of the atypical autosomal recessive lysosomal storage disorder, pycnodysostosis. Osteoclast cells in individuals with the CTSK protein exhibit abnormal type 1 collagen degradation and a buildup of undigested collagen fibers within lysosomes. The consequence is increased bone density, brittle bones, and a reduced stature.
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