https://www.selleckchem.com/pr....oducts/mk-8353-sch90
Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking. In a phase 2, double-blind, randomized, controlled trial involving patients with long-standing, moderate-to-severe major depressive disorder, we compared psilocybin with escitalopram, a selective serotonin-reuptake inhibitor, over a 6-week period. Patients were assigned in a 11 ratio to receive two separate doses of 25 mg of psilocybin 3 weeks apart plus 6 weeks of daily placebo (psilo