https://www.selleckchem.com/pr....oducts/zunsemetinib.
In this preclinical investigation, the feasibility of using diffusion tensor imaging (DTI) to study contrast-induced acute kidney injury (CIAKI) is explored, comparing radiographic outcomes with histopathologic and immunohistochemical findings after repeated animal exposures to iodinated contrast agent. Forty-five male wistar rats were allocated to three groups ( = 15 each), each receiving two separate injections 1 day apart group 1 (iodixanol then saline); group 2 (iodixanol twice); and control group (saline twice). Five rats were