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The clinical usefulness of computer-aided detection of cerebral aneurysms has been investigated using different methods to present lesion candidates, but suboptimal methods may have limited its usefulness. We compared three presentation methods to determine which can benefit radiologists the most by enabling them to detect more aneurysms. We conducted a multireader multicase observer performance study involving six radiologists and using 470 lesion candidates output by a computer-aided detection program, and compared the following three different presentati