https://www.selleckchem.com/products/lys05.html
In many eukaryotes, Argonaute proteins, guided by short RNA sequences, defend cells against transposons and viruses. In the eubacterium Thermus thermophilus, the DNA-guided Argonaute TtAgo defends against transformation by DNA plasmids. Here, we report that TtAgo also participates in DNA ****tion. In vivo, TtAgo binds 15- to 18-nt DNA guides derived from the chromosomal region where ****tion terminates and associates with proteins known to act in DNA ****tion. When gyrase, the sole T. thermophilus type II topoisomerase, is inhibi
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