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Contrast-enhanced ultrasonography (CEUS) is increasingly being performed in Italy and Europe, particularly in the field of hepato-gastroenterology. Initially, it was mainly carried out to characterize focal hepatic lesions, but, since then, numerous studies have demonstrated its efficacy in the differential diagnosis of focal pancreatic pathologies (D'Onofrio et al. in Expert Rev Med Devices 7(2)257-273, 2010; Vidili et al. in J Ultrasound 22(1)41-51, 2019). The purpose of this paper is to provide Italian Medical Doctors with recommenda