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001) and radiotherapy (p = 0.007). Liver-specific SSI risk factors were smoking (p = 0.046), low albumin (p 0.001) and significant blood loss (p 0.001). The rate of organ/space SSI in patients with POPF was 47.7% and in patients without POPF 7.3% (p 0.001). Organ/space SSI rate was 43% in patients with bile leak and 10% in those without (p 0.001). The risk factors for SSI following pancreatic and liver resections are distinct from each other, with higher SSI rates after pancreatic resection. Pancreaticoduodenectomy has increased risk of