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TNFSF11 expression levels were markedly higher in non-LP samples than in LP samples among premenopausal women, as indicated by a significant area under the curve (AUC 0.80, 95% CI 0.70, 0.91). Including histomorphological data did not result in a substantial improvement in the prediction of non-LP versus LP samples (AUC 0.87, 95% CI 0.78, 0.96). Premenopausal subjects exhibited improved prediction of lymphocytic pleocytosis in reactive meningitis