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Using a generalized linear mixed model, significant increases in positive emotions and daily spiritual experiences, and reductions in perceived stress and heart rate were found in the experimental group compared to the other two groups. Tamarkoz seems to show some advantages over the usual stress management resources offered by a student health center.Trial registration ClinicalTrials.gov Protocol Registration Date (03/04/2018); ClinicalTrials.gov ID NCT03489148.The number of secondary cases, i.e. the number of new infections generated