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The mean acini area of one meibomian gland was 0.088±0.025mm in young mice and 0.080±0.020mm in old mice (p=0.564), but the Meibomian gland density was significantly lower in older mice (41.7±6.4%, 27.3±4.2%) (p=0.021). We have developed an in vivo meibography device that may prove useful in sequentially documenting changes during development of meibomian gland dysfunction and following treatment. We have developed an in vivo meibography device that may prove useful in sequentially documenting changes during development of meibomian gl
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