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The Kilroy spring showed a greater total displacement (465.60 μm) on the impacted canine. The higher stresses on the adjacent lateral (5.29 kPa) and premolar (6.41 kPa) occurred with the Kilroy spring. Conclusions The Kilroy spring yielded higher stresses than the NiTi closed-coil spring on the impacted canine and the adjacent teeth. The difference between distribution of the stresses over the impacted canine induced greater displacement with the Kilroy spring, particularly in the vertical direction.Gene annotation is a critical bottleneck