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To provide therapeutic window of amisulpride dose and serum concentration. 194 schizophrenics were assessed with PANSS. The concentration of Amisulpride in blood was tested. And relationship with concentration was analyzed. The dose of amisulpride was 100mg∼1200 mg/d(555+/-218), plasma concentration was 20∼1280 ng/mL(349+/-223) and C/D ratio was 0.07∼1.65 (0.63+/-0.34). The correlation of dose and concentration was significantly correlated (r = 0.55; P 0.05).It was found that concentration(P 0.001), C/D ratir = 0.383, P 0.001), rather than
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