https://www.selleckchem.com/sc....reening-libraries.ht
1-100_1-79dup and TERTp c.1-110_1-89, respectively. TERTp duplications (TERTpdup) mainly affected the binding capacity of two transcription factors' families, i.e. the members of the E-twenty-six and the Specificity Protein/Krüppel-Like Factor groups. In fact, these new TERTpdup significantly enhanced the E-twenty-six transcription factors' binding capacity, which is also typically increased by the two c.1-124 C T/c.1-146 C T hotspot TERTpmut. On the other hand, they were distinguished by enhanced affinity for the Krüppel p
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