https://www.selleckchem.com/pr....oducts/ac-fltd-cmk.h
This study demonstrated the potential mechanism of m6A modification in metastasis and provided potential targets for treatment in TNBC.Quinacrine has been identified as a potent DR5-inducing agent that sensitizes cancer cells to TRAIL-induced apoptosis. In the current study, we found that quinacrine increased DR5 mRNA levels significantly in ovarian cancer cell lines regardless of p53 status. Further study showed the half-life of DR5 in quinacrine-treated cells was significantly prolonged, indicating that DR5 protein degradation was