https://www.selleckchem.com/pr....oducts/zilurgisertib
The presence of genome scale RNA secondary structure (GORS) was the only other genomic or structural parameter significantly associated with C-U/U-C transition asymmetries by multivariable analysis (ANOVA), potentially reflecting RNA structure dependence of sites targeted for C-U mutations. Using the association index metric, C-U changes were specifically over-represented at phylogenetically uninformative sites, potentially paralleling extensive homoplasy of this transition reported in SARS-CoV-2. Although