https://www.selleckchem.com/pr....oducts/Phlorizin(Phl
For mice administrated with berberine, cancellous bone mass was upregulated in a dose-dependent manner, as indicated by gradually increased bone mass, trabecular bone volume fraction and trabecular number. Furthermore, berberine promotes osteogenic and inhibits adipogenic differentiation of BMSCs via cAMP/PKA/CREB signaling. Also, bone resorption effect becomes more obvious with increasing dose of berberine in vitro. The present results suggest that berberine exerts potent bone protective effects by promoting bone formatio
Like
Comment
Share
