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Fetal T2S actively transits to the mother's system via placental exchange, and the maternal levels of T2S or its metabolite, W-Compound, are indicative of fetal thyroid activity. In this manner, W-Compound found in maternal serum might indicate fetal thyroid function in utero, although further examination is needed to determine if it serves as a substitute technique for diagnosing and treating congenital hypothyroidism associated with disor
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