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A novel Mn-doped Fe-based metal-organic framework (MOF) Fenton-like catalyst was prepared for the removal of wastewater organic pollutants. The catalyst exhibited good degradation performance, stability, and recyclability for the removal of phenol from water with a maximum catalytic efficiency of 96%. Incorporating a long persistent phosphor in the MOF ensured optimum performance in the dark.A series of novel α-furfuryl-2-alkylaminophosphonates have been efficiently synthesized from the one-pot three-component classical Kabachnik-Fields