https://www.selleckchem.com/pr....oducts/brefeldin-a.h
CF patients with low fractionally exhaled NO (FENO) showed lower plasma Arg and nitrate concentrations. During acute exacerbation, sputum Arg and hArg levels were high and dropped after antibiotic treatment Arg pre-antibiotics 4.14 nmol/25 mg sputum vs. post-antibiotics 2.33 nmol/25 mg sputum, p = 0.008; hArg pre-antibiotics 0.042 nmol/25 mg sputum vs. post-antibiotics 0.029 nmol/25 mg sputum, p = 0.035. The activated Arg/NO metabolism in stable CF patients may be a result of chronic inflammation. PSA infection did not play a major
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