https://www.selleckchem.com/pr....oducts/elenbecestat.
BACKGROUND A physiological small animal model that resembles COVID-19 with low mortality is lacking. METHODS Molecular docking on the binding between angiotensin-converting enzyme 2 (ACE2) of common laboratory mammals and the receptor-binding domain of the surface spike protein of SARS-CoV-2 suggested that the golden Syrian hamster is an option. Virus challenge, contact transmission, and passive immunoprophylaxis were performed. Serial organ tissues and blood were harvested for histopathology, viral load and titre, chemokine/cytoki
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