https://www.selleckchem.com/pr....oducts/i-bet151-gsk1
The most plausible explanation for this spectrum of phenotypic outcomes is that FMF regulate growth factor signalling essential for proper growth and homoeostasis of the skin. Here, we will give an overview about the current understanding of the underlying pathomechanisms leading to fibrillin-dependent fibrosis as well as forms of cutis laxa caused by mutational inactivation of FMF-associated ligands. Endometriosis is a long-term condition in which endometrial-like tissue grows outside of the womb, causing intense chronic p