https://jhu395antagonist.com/r....elationship-among-ag
The role of Tanshinone IIA (TIIA) in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) was examined in this study, scrutinizing the related mechanisms. Employing the collagen-induced arthritis (CIA) protocol, we developed a murine model of rheumatoid arthritis. To investigate the in vivo and in vitro effects of TIIA on CIA mice and RA-FLSs, gain- or loss-of-function manipulations were performed on matrix metalloproteinase 9 (MMP9), rec