https://Mad2signals.com
Currently, oligonucleotide therapy has been established as a revolutionary method in the treatment of human diseases. Despite their potential, therapeutic oligonucleotides frequently require modifications prior to direct use in numerous instances. To optimize the performance of therapeutic oligonucleotides, including their stability, specificity, affinity, inhibitory characteristics, and delivery, chemical modification or conjugation is frequently employed. A recent proposal for a conjugation method focused on a 15-nucleotide G-quadruplex thrombin aptamer, with
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