https://www.selleckchem.com/pr....oducts/ro5126766-ch5
The clinical course of COVID-19 is very heterogeneous most infected individuals can be managed in an outpatient setting, but a substantial proportion of patients requires intensive care, resulting in a high rate of fatalities. We performed a biomarker study to assess the impact of prior infections with seasonal coronaviruses on COVID-19 severity. Sixty patients with confirmed COVID-19 infections were included (age 30-82; 52 males, 8 females) 19 inpatients with critical disease, 16 inpatients with severe or moderate disease,