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This overview highlights the development and applications of GNS-mediated therapy developed in our laboratory for cancer treatment. This paper also presents recent results of experimental studies to illustrate the superior performance of GNS for photothermal treatment applications.The article presents an analysis of the nature and causes of changes observed in the long economic cycles (Kondratieff waves) of global economic development of the first half of the 21st century. The forms of these modifications and the time bou