https://mirnamimic.com/index.p....hp/mettl3-counteract
The loss of 5-methylcytosine oxidases and the malfunction of the RYBP Polycomb component in bronchial cells promote a widespread hypermethylation of CpG islands, inducing tumor formation, resembling alterations observed in human lung tumors. The 45-dihydro-12,4-oxadiazole, a five-membered N-O heterocycle, was identified as a single nitrogen atom transfer agent, facilitating the removal of a ketone/aldehyde and a nitrile. This reagent enabled the successful applicatio