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risk assessment before hepatic resection using routine laboratory parameters. Surgical-site complications (SSCs) remain a significant cause of morbidity and mortality, particularly in high-risk patients. The aim of this study was to determine whether prophylactic use of a specific single-use negative-pressure wound therapy (sNPWT) device reduced the incidence of SSCs after closed surgical incisions compared with conventional dressings. A systematic literature review was performed using MEDLINE, Embase and the Cochrane Library to identi