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A multivariate analysis revealed odds ratios for tumor volumes (0.64; 95% confidence interval (CI), 0.46-0.89; P=.008), solid volume percentages (0.96; 95% CI, 0.93-0.99; P=.024), skewness (3.45; 95% CI, 1.38-8.65; P=.008), and entropy levels (0.21; 95% CI, 0.07-0.58; P=.003). The area under the receiver operating characteristic curve was 0.90 (95% CI, 0.85-0.94) for the optimal model containing these 4 variables, with 85% sensitivity and 79% specificity. Voxel-based histogram analysis of 3-dimensional computed tomography images accurate