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What Happens When You Change Your Invisalign Trays? During Invisalign tray changes, you can expect some slight discomfort or pressure as the aligners work to shift your teeth into the desired position. This is normal and is a sign that the treatment is progressing. It is important to wear each set of trays for the recommended time period, usually about 1-2 weeks, before moving on to the next set. When you switch to a new set of aligners, you may also notice that