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It is necessary to determine the botanical and geographic source of wine to combat fraud and assess its quality. A combination of 1H NMR profiling and chemometrics permits the precise measurement of 31 prevalent organic constituents within the NMR spectra of 70 diverse wines. A successful differentiation of Bulgarian and international wine varieties, based on their NMR metabolomic profiles, was accomplished using linear discriminant analysis. Typical local grape varietal wines exhibit higher average concentrations of galacturonic