https://www.selleckchem.com/pr....oducts/nazartinib-eg
These two MoA converge in a novel putative Adverse Outcome Pathway (AOP) network on the key event (KE) hypomyelination. Comparative analyses of human and rat neural progenitor cells (NPCs) revealed that human oligodendrogenesis is more sensitive to endocrine disruption by TBBPA. Therefore, we emphasize that ethical, cost-efficient and species-overarching in vitro assays are needed for DNT hazard assessment. By incorporation of large-scale transcriptomic analyses, we brought the NPC6 assay to a higher readiness level fo
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