https://www.selleckchem.com/pr....oducts/diphenhydrami
The frequency in 453 Spanish controls was of 0.22%; similar to that observed in 51,343 non-Finnish European GnomAD population (0.24%). We found an almost statistically significant association of truncating ERCC3 variants with BC (odds ratio [OR]=2.25, confidence interval [CI]=0.6-5.93,P=0.11), and we observed for the first time a significant association with OC (OR=4.74, CI=1-14.34,P=0.028), that holds even after removing MINAS cases. To our knowledge, this is the largest HBOC series comprehensively analysed for ERCC3 mutations,