https://www.selleckchem.com/pr....oducts/rbn013209.htm
Transcription factor (TF) DNA-binding is a central mechanism in gene regulation. Biologists would like to know where and when these factors bind DNA. Hence, they require accurate DNA-binding models to enable binding prediction to any DNA sequence. Recent technological advancements measure the binding of a single TF to thousands of DNA sequences. One of the prevailing techniques, high-throughput SELEX, measures protein-DNA binding by high-throughput sequencing over several cycles of enrichment. Unfortunately, current computational meth