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Eighteen-month-old Angus steers, four weighing 472 kg and four weighing 48 kg, were randomly distributed into monensin (5 steers) and ProTect (5 steers) groups, and were incrementally exposed to grain diets formulated with either monensin or ProTect for a 36-day period. Diet compositions varied progressively; a 7-day starter diet (45% grain), followed by T1 (7 days; 56% grain), T2 (7 days;