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939; sensitivity 76.74%; specificity 96.67%; cut-off value 231×10-9, P less then 0.001). Furthermore, nNO levels were associated with CRSwNP endotypes(odds ratio 1.010; 95% confidence interval 1.003%, 1.016%; P=0.002). When the nNO concentration was 158 ×10-9, we could discriminate Eos CRSwNP from non-Eos CRSwNP(AUC=0.710, sensitivity 76.92%; specificity, 60.47%, P=0.001). After it was combinated by nNO, periphera blood eosinophil count(PEAC) and VAS score, the AUC was increased to 0.894(95%CI=0.807 to 0.951, P less then 0.000 1, sen