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CONCLUSION These results highlight the need for prompt diagnosis and intensive therapeutic intervention from disease onset in ARFID. © 2020 Wiley Periodicals, Inc.The mammalian central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN contains multiple circadian oscillators which synchronize with each other via several neurotransmitters. Importantly, an inhibitory neurotransmitter, γ-amino butyric acid (GABA), is expressed in almost all SCN neurons. In this review, we discuss how GABA influe