https://www.selleckchem.com/pr....oducts/alofanib-rpt8
Unlike bacteria, mammalian cells need to complete DNA ****tion before segregating their chromosomes for the maintenance of genome integrity. Thus, cells have evolved efficient pathways to restore stalled and/or collapsed ****tion forks during S-phase, and when necessary, also to delay cell cycle progression to ensure ****tion completion. However, strong evidence shows that cells can proceed to mitosis with incompletely ****ted DNA when under mild ****tion stress (RS) conditions. Consequently, the incompletely repl
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