https://www.selleckchem.com/pr....oducts/apx-115-free-
Background Polygenic risk scores (PRS) for coronary artery disease (CAD) identify high-risk individuals more likely to benefit from primary prevention statin therapy. Whether polygenic CAD risk is captured by conventional paradigms for assessing clinical cardiovascular risk remains unclear. Objectives This study sought to intersect polygenic risk with guideline-based recommendations and management patterns for CAD primary prevention. Methods A genome-wide CAD PRS was applied to 47,108 individuals across 3 U.S. health care syst
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