https://www.selleckchem.com/products/kpt-9274.html
A novel alkynyl phosphane gold(I) complex (trimethylphosphane)(3-(1,3-dimethylxanthine-7-yl)prop-1-yn-1yl)gold(I) 1 displayed mutiple biological acitivites including selective proliferation inhibitory, anti-metastatic and anti-angiogenic effects. The complex also induced effects related to aneuploidy in HCT-116 colon carcinoma cells, which might be mainly ascribed to the dysfunction of mitochondrial bioenergetics and downregulation of glycosis. Induction of aneuploidy beyond a critical level can provide an effective strategy to target
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