https://www.selleckchem.com/pr....oducts/PF-2341066.ht
Insect-specific flaviviruses (ISFs) have been isolated from a range of mosquito species from different parts of the world. These viruses ****te efficiently in mosquitoes but do not appear to ****te in vertebrates. There is increasing evidence that ISFs persist in nature through vertical transmission, and that they interfere with the ****tion and transmission of pathogenic flaviviruses in the mosquito host. A novel ISF species, Parramatta River virus (PaRV), was previously shown to occur at high rates in Aedes (Ae.) vigilax m