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013 and = 0.001) after curative resection displayed poorer overall survival and higher recurrence rates following RFA. On multivariate analyses, the pathologic tumor grade ( = 0.026 and = 0.038) and recurrence-free survival after primary curative resection ( = 0.028 and 0.001) emerged as independent risk factors of survival and HCC recurrence. Primary tumor differentiation and time to recurrence after curative resection are viable prognostic factors of overall survival and further recurrence risk in patients undergoing